favism

biochemistry

2nd paper

killer subject

4 & 5 July 2011

4th of July

exam written

60 MCQs , 45 marks

mcq nye boleh tahan lahhh

walaupun ade yg konpius2. (kalo x konpius, bukan biochem lah kan ? )

essay

seperti yang dikhabarkan

keluar lah gak akhirnya soalan cases

agak susah disitu

tapi bantai saje

pukul 12 da stop membantai

termenung tgok dak2 nigeria dgn skill meniru yg hebat

(nak kuar dewan exam awal nti org ckp bajet pandai lak kann)

5th of July

oral exam

khabar angin (lagi) mengatakan exam start pukul 9 pagi

tp mendapat khabar yg takbaik oleh orang yg pg awal

exam dah start pukul 8

kelam kabut beb

nasib baik doc x ikot nombor

lalu bersiap dengan pantas menahan teksi ke ain shams

sampai department biochemistry , amek kad tertulis , lajnah 4

tnggu punya tunggu luar bilik doctor

lalu kuarlah doctor Farid dan tanye ,

lajnah 4 ? owh aku tu.

aku pun berlalu masuk dalam bilik doctor.(kenape dah mcm novel plak ayat nih)

D = Doctor Farid

I = Dr Is Afiq (ecehh)

I = assalamualaikum . how are you , doctor ? (kali ni kene start dgn positif.xnak jd macam physio lepas)

D = fine. alhamdulilah. how was your exam yesterday ?

I = err.. nus-nus. (ni ayat paling best aku setakat 6 oral exam nih.haha)

D = nus-nus ? it was difficult ?

I = quite difficult. especially the cases.

D = what question came out in your exam yesterday ?

I = cholesterol. (alamak.aku terperangkap.mati aku kalau doctor tanye balek pasal exam semalam)

D = only cholesterol come out in the exam ?

I = ouh , no. we also have questions on vitamin D and favism.

D = favism is really important because it can lead to hemolysis of RBCs. what do you know about hemolysis ?

I = (knape mcam soalan physio 1st year nih) Hemolysis is the rupture of RBCs and release of its content.

D = yes. and what factors can lead to its rupture. maybe because of its membrane. do you know anything that can maintain the membrane's integrity?

I = yes. its glutathione.

D = glutathione ,good . and why this disease will lead to hemolysis of RBC ?

I = favism , which is defiency of glucose 6 phosphate dehydrogenase is important for red blood cell. this enzyme involved in HMP pathway , which produces NADP+P. NADP+P is important for glutathione for its conversion. that is why deficiency of this enzyme will lead to rupture of red blood cell. (time suruh explain by words susah plak semalam.haishh) 

D = yes , good. ok , calcitonin is one of the hormones in our body. what is its function ?

I = its main function is to regulate blood calcium level. it decreases blood calcium in the blood.

D = what is its mechanism of action ?

I = hmm. (bagus soalan ni.tp aku terdiam. cmne jwpan dalam konsep biochem eh. kang aku bg jwpan cam dalam buku physio kang)

D = ok , look . where does this calcium comes from ?

I = bones.

D = yes , so calcitonin decreases calcium level by formation of bone.

I = yessss. (ouh cmtu ke.haha.same macam physio lah.ngokngek tol aku)

D = tell me what increases calcium level in the blood.

I = parathyroid hormone and active vitamin D.

D = yes. ok , methionine is very important amino acid in our body. do you know its function ?

I = yes. methionine , in its active form , S-adenosyl methionine (SAM) is important in transmethylation reaction. for example , the formation of epinephrine from norepinephrine , melatonin from serotonin , choline from serine , and ..

D = ok , that is enough . now tell me what is the difference between type-1 diabetes mellitus (DM) and type-2.

I = type-1 DM is insulin dependent DM (IDDM) . it is mainly due to lack of formation of insulin by b-cells of pancreas. while type 2 is non-insulin dependent DM (NIDDM) . its maybe due to insulin resistance in our body. it mainly occur in obese people. Type 1 occurs in young people while type 2 in old people. 

D = ok. tell me the chronic complications of DM.

I = the patient will suffer from hyperglycemia and ketosis. if we treat them with overdose of insulin, they may be hypoglycemic as well.

D = what happened to the central nervous system? and their eyes ?

I = there will be neurological manifestation (neuropathy) . and cataract will develop in their eyes , due to accumulation of sugar alcohol .

D = ok . thank you. you may go now.

oral exam ni betul2 buat gua rase macam doctor yg tngah explain kat patient

ape2 pun tarik nafas lega

alhamdulilah

subject paling membunuh selesai gak akhirnya

14 & 16 July 

head & neck . abdomen . neuroanatomy . pelvis . special embryology . 

all the best untuk semua ! :)